Marketing authorisation number s 9. No long term studies have been conducted in animals to determine whether cyclizine has a potential for carcinogenesis. Hypersensitivity to the active substance or to any of the excipients listed in section 6. System Organ Class Frequency Adverse reactions Blood and lymphatic system disorders Not known Agranulocytosis, leucopenia, haemolytic anaemia, thrombocytopenia. Clear colourless and free from visible particles solution for injection.
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It allows the continuous delivery of a range of therapies to aid patient comfort. The exact mechanism by which cyclizine can prevent or suppress both nausea and vomiting from various causes is unknown. Hypersensitivity to the active substance or to any of the excipients listed in section 6. Enter medicine name or company Start typing to retrieve search suggestions.
Used in bowel spasm or ureteric colic. For the prevention of postoperative nausea and vomiting, administer the first dose by slow intravenous injection 20 minutes before the anticipated end of surgery.
Cyclizine Lactate 50 mg/ml Injection
For the full list of excipients, see dise 6. Valoid enhances the soporific effect of pethidine. Cyclizine is contraindicated in the presence of acute alcohol intoxication.
When used intravenously, Cyclizine Injection should be injected slowly into the bloodstream, with only minimal withdrawal of blood into the syringe.
Reporting suspected adverse reactions after authorisation of the medicinal product is important. Disorientation, restlessness or agitation, nervousness, euphoria, insomnia and auditory and visual hallucinations have been reported, particularly when dosage recommendations have been exceeded.
Pain is experienced by most patients with advanced cancer. Injection site reactions including vein tracking, erythema, pain, thrombophlebitis and blisters.
Cyclizine Lactate 50 mg/ml Injection – Summary of Product Characteristics (SmPC) – (eMC)
In the management of acute overdosage with cyclizine, gastric lavage and supportive measures for respiration and circulation should be performed if necessary. For the prevention of postoperative nausea and vomiting, administer the first dose by slow intravenous injection 20 minutes before the anticipated end of surgery.
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Active ingredient cyclizine lactate. Drug and Indication Dose Other Comments Diamorphine for pain If the patient is not receiving oral morphine, mg per 24 hours, or total cclizine dose in mg in last 24 hours divided by 3.
Anaphylaxis has been recorded following intravenous administration of cyclizine co-administered with propanidid in the same syringe.
Increase dose by one third if pain persists. Hypersensitivity reactions, including anaphylaxis have occurred. Eye disorders Not known Blurred vision, oculogyric crisis Gastrointestinal system disorders Not known Dryness of the mouth, nose and throat, constipation, increased gastric reflux, nausea, vomiting, diarrhoea, stomach pain, loss of appetite.
Symptoms of acute toxicity from cyclizine arise from peripheral anticholinergic effects and effects on the central nervous system. Valoid is indicated in adults for the prevention and treatment of nausea and vomiting including: Valoid may counteract the haemodynamic benefits of opioid analgesics.
You may find the End of Life Care article more useful, or one of our other health articles. Carcinogenic potential No long term studies have been conducted in animals to determine whether cyclizine has a potential for carcinogenesis. A sensation of heaviness, chills and pruritus have been reported rarely.
Cyclizine may counteract the haemodynamic syrknge of opioid analgesics.